Medical Implications of Antimicrobial Coating Polymers- Organosilicon Quaternary Ammonium Chloride
نویسندگان
چکیده
منابع مشابه
Percutaneous absorption of an antimicrobial organosilicon quarternary ammonium chloride in rabbits.
The percutaneous absorption of an organosilicon quaternary ammonium chloride (14C)-3-(trimethoxysilyl)-propyldimethyloctadecyl ammonium chloride (14C-Si-QAC) was studied in rabbits. Aqueous solution of 14C-Si-QAC was either applied to the intact, clipped back of animals for 10 days or administered by a single intravenous dose. Urine and feces were collected at 24-h intervals and tissue concentr...
متن کاملNon-leaching antimicrobial surfaces through polydopamine bio-inspired coating of quaternary ammonium salts or an ultrashort antimicrobial lipopeptide
Bacterial fouling on surfaces significantly increases the resistance of bacteria toward antibiotics, which leads to medical complications and a corresponding financial burden. Here, we report on a general and robust technique for facile modification of various surfaces with different antibacterial agents. Our approach in this study was inspired by the strong adhesion of mussel adhesion proteins...
متن کاملSynthesis and antimicrobial activity of quaternary ammonium silane coupling agents.
Fourteen novel silane coupling agents with a quaternary ammonium group introduced into the molecule, [CH(2)=CHCH(2)N(+)(CH(3))(C(n)H(2n+1))(CH(2))(3)Si(OCH(3))(3)]X(-) (n-X, n=10-18, X=Cl, Br, or I), were synthesized with the aim of using these agents to make material surfaces antimicrobial for a long period of time. Measurements of the minimum inhibitory concentrations (MIC) against 12 kinds o...
متن کاملAntimicrobial Polymeric Materials with Quaternary Ammonium and Phosphonium Salts
Polymeric materials containing quaternary ammonium and/or phosphonium salts have been extensively studied and applied to a variety of antimicrobial-relevant areas. With various architectures, polymeric quaternary ammonium/phosphonium salts were prepared using different approaches, exhibiting different antimicrobial activities and potential applications. This review focuses on the state of the a...
متن کاملQuaternary ammonium N,N-dichloroamines as topical, antimicrobial agents.
A series of backbone modified and sulfonic acid replacement analogs of our topical, clinical candidate (iii) were synthesized. Their antimicrobial activities and aqueous stabilities at pH 4 and pH 7 were determined, and has led us to identify quaternary ammonium N,N-dichloroamines as a new class of topical antimicrobial agents.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Modern Chemistry & Applications
سال: 2013
ISSN: 2329-6798
DOI: 10.4172/2329-6798.1000107